Your Name: Ellen Dean

Theme: Coagulation

OPTION LIST

A

Activated factor X

I

Tissue factor

B

Arachidonic acid

J

Tissue factor pathway inhibitor

C

Cyclooxygenase

K

Vascular endothelium

D

Factor VII

L

Vascular subendothelium

E

Platelets

M

  

F

Protein C

N

  

G

Protein S

O

  

H

Thrombin

P

  

For each scenario below, choose the most appropriate answer from the list above. Each option may be used once, more than once or not at all.

1. Which protein, important in haemostasis, is vitamin K dependent but is not a serine protease?

 

2. Which option is required as a cofactor for protein C activity?

 

3. Which option synthesises tissue factor, vWF, prostacyclin, plasminogen activator, antithrombin III and thrombomodulin?

 

4. Which enzyme, important for platelet aggregation, is irreversibly inhibited by aspirin?

 

5. Which key clotting factor activates both factors V and VIII, and also activates protein C?

 

ANSWERS

1. G

2. G

3. K

4. C

5. H